Investigation of Structure and Electric Study of Calcium Silicate/Chitosan Composite Pre- and Post-Immersion in SBF

Authors

Khaled R. Mohamed, Department of Refractories, Ceramics and Building Materials, Laboratory of Biomaterials, National Research Centre, 33 El-Buhouth St., Dokki, Giza, P.O. 12622, EgyptFollow
Mohamed M. M. Elnasharty, Microwave Physics and Dielectrics Dep., National Research Centre, 33 El Bohouth St., Dokki, P.O.12622, Giza, EgyptFollow
Mostafa I. Abdelglil, College of Medical Technical, Department of Medical Laboratory Techniques, Al-Farahidi University, Jadriya Bridge, P.O.10011 Baghdad, IraqFollow
Ragab M. Mahani, Microwave Physics and Dielectrics Dep., National Research Centre, 33 El Bohouth St., Dokki, P.O.12622, Giza, EgyptFollow

Abstract

The main goal of this article was to determine whether calcium silicate/chitosan composite as a bone graft material to facilitate autogenous bone formation. We investigated the structure, morphology, weight loss, and dielectric properties of the fabricated composites pre-immersion (control) and post-immersion in stimulated body fluids (SBF) for 7 and 28 days using various techniques. FTIR, TGA, and SEM analysis prove the formation of a composite from calcium silicate integrated with chitosan polymer. The bone-like apatite layer formed after 7 days and improved after 28 days. TGA tests showed that sample 28 kept more material (38.24%) than 7 (25.88%) and control sample C (22.75%), leading to the soaking adding minerals to the composite or changing its structure. Dielectric studies over a frequency range (0.1 Hz–10 MHz) showed lower permittivity values in the post-immersion in SBF for 28 days than their counterparts of the control sample, confirming the formation of a thick apatite layer (adsorbing Ca²⁺ and PO^3–) on the composite surface. Accordingly, the fabricated composite could be useful as a bone grafting material due to its bioactivity. Furthermore, the permittivity of this composite changed with the orientation of OH- ions in apatite crystals, which might be useful in the apatite formation process and bone tissue engineering in the future.

Recommended Citation

Mohamed, Khaled R.; Elnasharty, Mohamed M. M.; Abdelglil, Mostafa I.; and Mahani, Ragab M. (2025) "Investigation of Structure and Electric Study of Calcium Silicate/Chitosan Composite Pre- and Post-Immersion in SBF," Al-Farahidi Biomedical Journal: Vol. 1: Iss. 1, Article 2.
Available at: https://fbmj.uoalfarahidi.edu.iq/journal/vol1/iss1/2